点云识别是工业机器人和自主驾驶中的重要任务。最近，几个点云处理模型已经实现了最先进的表演。然而，这些方法缺乏旋转稳健性，并且它们的性能严重降低了随机旋转，未能扩展到具有不同方向的现实情景。为此，我们提出了一种名为基于自行轮廓的转换（SCT）的方法，该方法可以灵活地集成到针对任意旋转的各种现有点云识别模型中。 SCT通过引入轮廓感知的转换（CAT）提供有效的旋转和翻译不变性，该转换（CAT）线性地将点数的笛卡尔坐标转换为翻译和旋转 - 不变表示。我们证明猫是一种基于理论分析的旋转和翻译不变的转换。此外，提出了帧对准模块来增强通过捕获轮廓并将基于自平台的帧转换为帧内帧来增强鉴别特征提取。广泛的实验结果表明，SCT在合成和现实世界基准的有效性和效率的任意旋转下表现出最先进的方法。此外，稳健性和一般性评估表明SCT是稳健的，适用于各种点云处理模型，它突出了工业应用中SCT的优势。

Computer-aided systems in histopathology are often challenged by various sources of domain shift that impact the performance of these algorithms considerably. We investigated the potential of using self-supervised pre-training to overcome scanner-induced domain shifts for the downstream task of tumor segmentation. For this, we present the Barlow Triplets to learn scanner-invariant representations from a multi-scanner dataset with local image correspondences. We show that self-supervised pre-training successfully aligned different scanner representations, which, interestingly only results in a limited benefit for our downstream task. We thereby provide insights into the influence of scanner characteristics for downstream applications and contribute to a better understanding of why established self-supervised methods have not yet shown the same success on histopathology data as they have for natural images.

Large language models (LLMs) have been shown to be able to perform new tasks based on a few demonstrations or natural language instructions. While these capabilities have led to widespread adoption, most LLMs are developed by resource-rich organizations and are frequently kept from the public. As a step towards democratizing this powerful technology, we present BLOOM, a 176B-parameter open-access language model designed and built thanks to a collaboration of hundreds of researchers. BLOOM is a decoder-only Transformer language model that was trained on the ROOTS corpus, a dataset comprising hundreds of sources in 46 natural and 13 programming languages (59 in total). We find that BLOOM achieves competitive performance on a wide variety of benchmarks, with stronger results after undergoing multitask prompted finetuning. To facilitate future research and applications using LLMs, we publicly release our models and code under the Responsible AI License.

具有可穿戴设备的人类活动识别（HAR）是有希望的研究，可以在许多智能医疗保健应用中广泛采用。近年来，基于深度学习的HAR模型已取得了令人印象深刻的识别表现。但是，大多数HAR算法都容易受到多级窗口问题的影响，而多级窗口问题是必不可少的但很少被利用的。在本文中，我们建议通过将细分技术引入HAR来缓解这个具有挑战性的问题，从而产生共同的活动细分和认可。特别是，我们介绍了多个阶段的时间卷积网络（MS-TCN）体系结构，以进行样品级活动预测至关节段并识别活动序列。此外，为了增强HAR对阶层间相似性和阶层内异质性的鲁棒性，已经提出了一个多层次的对比损失，其中包含样本级别和段级对比度，以学习结构良好的嵌入空间的空间更好的活动细分和识别性能。最后，通过全面的实验，我们验证了对两个公共HAR数据集的拟议方法的有效性，从而实现了各种评估指标的重大改进。

由于形态的相似性，皮肤肿瘤的组织学切片分化为个体亚型可能具有挑战性。最近，基于深度学习的方法证明了它们在这方面支持病理学家的潜力。但是，这些监督算法中的许多都需要大量的注释数据才能进行稳健开发。我们提供了一个公开可用的数据集，该数据集是七个不同的犬皮肤肿瘤的350张全滑图像，其中有13种组织学类别的12,424个多边形注释，包括7种皮肤肿瘤亚型。在评估者间实验中，我们显示了提供的标签的高稠度，尤其是对于肿瘤注释。我们通过训练深层神经网络来进一步验证数据集，以完成组织分割和肿瘤亚型分类的任务。我们的肿瘤尤其是0.7047的类平均Jaccard系数为0.7047，尤其是0.9044。对于分类，我们达到了0.9857的幻灯片级准确性。由于犬皮肤肿瘤对人肿瘤具有各种组织学同源性，因此该数据集的附加值不限于兽医病理学，而是扩展到更一般的应用领域。

深度学习在开发新的医学图像处理算法方面获得了广泛的研究兴趣，并且在各种医学成像任务中，基于深度的基于学习的模型可以支持疾病检测和诊断。尽管取得了成功，但在医学图像分析中进一步改善了医学图像分析中的深度学习模型是由于缺乏大型和注释的数据集的缺乏。在过去的五年中，许多研究都集中在解决这一挑战。在本文中，我们审查并总结了这些最近的研究，以全面概述在各种医学图像分析任务中应用深度学习方法。特别是，我们强调了最先进的无监督和半监督深度学习在医学图像分析中的最新进展和贡献，这是根据不同的应用方案的总结，包括分类，分割，检测和图像登记。我们还讨论了主要的技术挑战，并提出了未来的研究工作中可能的解决方案。

Accurate determination of a small molecule candidate (ligand) binding pose in its target protein pocket is important for computer-aided drug discovery. Typical rigid-body docking methods ignore the pocket flexibility of protein, while the more accurate pose generation using molecular dynamics is hindered by slow protein dynamics. We develop a tiered tensor transform (3T) algorithm to rapidly generate diverse protein-ligand complex conformations for both pose and affinity estimation in drug screening, requiring neither machine learning training nor lengthy dynamics computation, while maintaining both coarse-grain-like coordinated protein dynamics and atomistic-level details of the complex pocket. The 3T conformation structures we generate are closer to experimental co-crystal structures than those generated by docking software, and more importantly achieve significantly higher accuracy in active ligand classification than traditional ensemble docking using hundreds of experimental protein conformations. 3T structure transformation is decoupled from the system physics, making future usage in other computational scientific domains possible.

We present a dynamic path planning algorithm to navigate an amphibious rotor craft through a concave time-invariant obstacle field while attempting to minimize energy usage. We create a nonlinear quaternion state model that represents the rotor craft dynamics above and below the water. The 6 degree of freedom dynamics used within a layered architecture to generate motion paths for the vehicle to follow and the required control inputs. The rotor craft has a 3 dimensional map of its surroundings that is updated via limited range onboard sensor readings within the current medium (air or water). Path planning is done via PRM and D* Lite.

Feature selection helps reduce data acquisition costs in ML, but the standard approach is to train models with static feature subsets. Here, we consider the dynamic feature selection (DFS) problem where a model sequentially queries features based on the presently available information. DFS is often addressed with reinforcement learning (RL), but we explore a simpler approach of greedily selecting features based on their conditional mutual information. This method is theoretically appealing but requires oracle access to the data distribution, so we develop a learning approach based on amortized optimization. The proposed method is shown to recover the greedy policy when trained to optimality and outperforms numerous existing feature selection methods in our experiments, thus validating it as a simple but powerful approach for this problem.

Deep neural networks are vulnerable to adversarial attacks. In this paper, we take the role of investigators who want to trace the attack and identify the source, that is, the particular model which the adversarial examples are generated from. Techniques derived would aid forensic investigation of attack incidents and serve as deterrence to potential attacks. We consider the buyers-seller setting where a machine learning model is to be distributed to various buyers and each buyer receives a slightly different copy with same functionality. A malicious buyer generates adversarial examples from a particular copy $\mathcal{M}_i$ and uses them to attack other copies. From these adversarial examples, the investigator wants to identify the source $\mathcal{M}_i$. To address this problem, we propose a two-stage separate-and-trace framework. The model separation stage generates multiple copies of a model for a same classification task. This process injects unique characteristics into each copy so that adversarial examples generated have distinct and traceable features. We give a parallel structure which embeds a ``tracer'' in each copy, and a noise-sensitive training loss to achieve this goal. The tracing stage takes in adversarial examples and a few candidate models, and identifies the likely source. Based on the unique features induced by the noise-sensitive loss function, we could effectively trace the potential adversarial copy by considering the output logits from each tracer. Empirical results show that it is possible to trace the origin of the adversarial example and the mechanism can be applied to a wide range of architectures and datasets.